GCSE Biology, Unit 3, Lesson 2 of 7

Defences and the immune system

GCSE Biology, Infection and response, 20 minutes

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The barriers that keep pathogens out, and how white blood cells destroy the ones that get in.

What you will learn

  • Describe how skin, nose, airways, stomach and tears keep pathogens out
  • Describe phagocytosis, antibodies and antitoxins
  • Explain why antibodies are specific
  • Read a primary and secondary response from an antibody graph

Keeping pathogens out

These non-specific defences work against any pathogen:

  • skin: a tough barrier
  • nose: hairs and mucus trap particles
  • trachea and bronchi: mucus traps pathogens and cilia sweep it up to the throat
  • stomach: hydrochloric acid kills pathogens in food
  • eyes: tears contain lysozyme, an enzyme that breaks down bacteria

The rest of this lesson and its 11 practice questions are locked.

In this lesson

  1. Keeping pathogens out
  2. White blood cells
  3. Meeting a pathogen twice
  4. Try it: Barriers first

11 practice questions, marked as you go; about 20 minutes in all.

Key terms

Non-specific, Cilia, Antigens, Memory cells, Immune, Vaccination

In this unit: Infection and response

Pathogens and how they spread, the body's defences and the immune system, vaccines, antibiotics and resistance, drug trials, and (Biology only) monoclonal antibodies and plant disease.

All of Infection and response