GCSE Biology, Unit 5, Lesson 7 of 8
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Negative feedback: thyroxine and adrenaline

GCSE Biology, Homeostasis and response, 25 minutes

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Higher: how the pituitary and thyroid hold thyroxine steady by negative feedback, reading TSH and thyroxine test results, and why adrenaline is a different kind of response.

What negative feedback means

Many levels in the body are held close to a set value: blood glucose, body temperature, water, and the hormone thyroxine.

In each case the body uses negative feedback: a change away from normal is detected, and the response pushes the level back the other way.

  1. A level changes (it rises or falls)
  2. The change is detected
  3. A response reverses the change
  4. The level returns to normal, and the response stops

Negative feedback always works against the change. If a response made the change bigger, it would not be negative feedback.

The rest of this lesson and its 12 practice questions are in Plus.

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  • 12 exam-style questions, marked as you go, each with a worked solution
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