GCSE Biology, Unit 2, Lesson 8 of 8

Cancer: tumours, risk factors and data

GCSE Biology, Organisation: tissues, organs, digestion and circulation, 25 minutes

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How tumours form, benign and malignant tumours and secondary tumours, lifestyle and genetic risk factors and carcinogens, tumour growth by cell division, and working with cancer data.

What you will learn

  • Describe cancer as uncontrolled cell growth and division
  • Compare benign and malignant tumours and explain how secondary tumours form
  • Name lifestyle and genetic risk factors and carcinogens for cancer
  • Calculate cell numbers after repeated divisions
  • Use cancer data to compare risk and to judge a causal link

How a tumour forms

Cancer is the result of changes in cells that lead to uncontrolled growth and division.

The cells divide by mitosis again and again, without the normal checks, and form a lump called a tumour.

  • Benign tumour: growths of abnormal cells contained in one area, usually within a membrane. They do not invade other parts of the body. They can still be harmful, for example by pressing on the brain.
  • Malignant tumour: a cancer. Its cells invade neighbouring tissues and can spread to different parts of the body in the blood, where they form secondary tumours.
  1. Tumour cells divide once every 24 hours, starting from 5 cells
  2. In 10 days: 10 × 24 = 240 hours; 240 ÷ 24 = 10 divisions
  3. Cells = 5 × 2¹⁰ = 5 × 1024 = 5120
  4. = 5.12 × 10³ cells

Each division doubles the number: multiply by 2 once for every division (2¹⁰), not by 2 × 10.

The rest of this lesson and its 10 practice questions are locked.

In this lesson

  1. How a tumour forms
  2. Risk factors and carcinogens
  3. Working with cancer data
  4. Try it: Benign or malignant?

10 practice questions, marked as you go; about 25 minutes in all.

Key terms

Cancer, Uncontrolled growth and division, Tumour, Secondary tumours, Ultraviolet light, Carcinogens, Ionising radiation

In this unit: Organisation: tissues, organs, digestion and circulation

Levels of organisation, digestion and enzymes with the amylase and food test practicals, the heart, blood and lungs, heart disease and cancer, and transport in plants.

All of Organisation: tissues, organs, digestion and circulation